William Stafford Noble (formerly William Noble Grundy) received the Ph.D. in computer science and cognitive science from UC San Diego in 1998. After a one-year postdoc with David Haussler at UC Santa Cruz, he became an Assistant Professor in the Department of Computer Science at Columbia University. In 2002, he joined the faculty of the Department of Genome Sciences at the University of Washington. His research group develops and applies statistical and machine learning techniques for modeling and understanding biological processes at the molecular level. Noble is the recipient of an NSF CAREER award and is a Sloan Research Fellow and a Fellow of the International Society for Computational Biology.