Genomic data visualization on the web

Wei Wu and William Stafford Noble

Bioinformatics. 20(11):1804-1805, 2004.


Many types of genomic data can be represented in matrix format, with rows corresponding to genes and columns corresponding to gene features. The heat map is a popular technique for visualizing such data, plotting the data on a two-dimensional grid and using a color scale to represent the magnitude of each matrix entry. Prism is a web-based software tool for quickly generating annotated heat map visualizations of genome-wide data. The tool provides a selection of genome-specific annotation catalogs, as well as a catalog upload capability. The generated heat maps are clickable, allowing the user to drill down to examine specific matrix entries, and gene annotations are linked to relevant genomic databases.

PRISM web page