Annotation results

SangerChip data, H4ac, HeLa, 64kb wavelet smooth data, 2-state segmentation

  • Number of segments
    • State 0: 61
    • State 1: 55
  • Total size (bp)
    • State 0: 16279939
    • State 1: 13577945
  • Avg. segment length
    • State 0: 266884
    • State 1: 246872
  • Median segment length
    • State 0: 183999
    • State 1: 183999
  • Minimum segment length
    • State 0: 22999
    • State 1: 999
  • Maximum segment length
    • State 0: 998999
    • State 1: 899999

Gene overlap

Bed files below contain one line for each gene whose Tx start sits inside the given state. Columns are chr, start, stop, gene ID, fraction of gene sitting inside the segment, strand, and segment ID

  1. KnownGene
  2. Gencode.Known
  3. Ensembl

Enrichment of various elements

Total number of bases or elements overlapping each state. Numbers in parentheses are the fractions of the element in that state. Second set of columns gives enrichment over expected (as a fraction). Enrichment p-values, computed by permuting state labels on the fixed segmentation, are also included, with adjusted p-values using method "BH".

Element                                                     st0                    st1     st0 enr    st0 enr p    st0 adj p     st1 enr    st1 enr p    st1 adj p
-------------------------                  --------------------   --------------------   ---------   ----------   ----------   ---------   ----------   ----------
Num_Gencode_TxStarts                                631 (0.223)           2202 (0.777)      -0.592            0            0       0.709            0            0
Num_mRNA_TxStarts                                   897 (0.186)           3938 (0.814)      -0.660            0            0       0.791            0            0
Num_Spliced.EST_TxStarts                          16819 (0.122)         121557 (0.878)      -0.777            0            0       0.932       0.0004    0.0008533
EST_Ovr                                         9166128 (0.471)       10297934 (0.529)      -0.136       0.0007       0.0014       0.163       0.0004    0.0008533
CpG.UCSC_Isl_Ovr                                  77550 (0.196)         317429 (0.804)      -0.640            0            0       0.767            0            0
RptMskr_Ovr                                     7251514 (0.540)        6167699 (0.460)      -0.009         0.31         0.31       0.011       0.2932       0.3027
RptMskr_DNA_Ovr                                  497692 (0.605)         324706 (0.395)       0.110       0.0064      0.01024      -0.132       0.0036       0.0064
RptMskr_LINE.L1_Ovr                             2676836 (0.642)        1494313 (0.358)       0.177       0.0004    0.0008533      -0.212       0.0001    0.0002667
RptMskr_LINE.L2_Ovr                              562403 (0.560)         442695 (0.440)       0.026       0.2903       0.3027      -0.031       0.2779       0.3027
RptMskr_LTR_Ovr                                 1391682 (0.665)         702644 (0.335)       0.219            0            0      -0.262            0            0
RptMskr_SINE.ALU_Ovr                            1284105 (0.336)        2542215 (0.664)      -0.385            0            0       0.461            0            0
SimpRep_Ovr                                      308453 (0.411)         442476 (0.589)      -0.247       0.0036       0.0064       0.296       0.0048     0.008084
MSA_strict_Ovr                                   322706 (0.450)         393623 (0.550)      -0.174       0.0234       0.0288       0.208       0.0182      0.02532
MSA_moderate_Ovr                                 700630 (0.474)         776003 (0.526)      -0.130       0.0262      0.03105       0.156       0.0199      0.02653
MSA_loose_Ovr                                   1747124 (0.495)        1780859 (0.505)      -0.092       0.0148      0.02153       0.110       0.0112      0.01707
MSA_non.exonic_Ovr                               576270 (0.640)         323625 (0.360)       0.174       0.0355      0.04057      -0.209       0.0219      0.02803

(Postscript version of above)

Distances of elements to segment boundaries

Results for each boundary

Average and median absolute value over all boundaries.

Statistic                                      avg(|d|)       med(|d|)
-------------------------                  ------------   ------------
Gencode_5P_Dist_Known                        1883228.16        21831.5
Gencode_3P_Dist_Known                        1886013.74        20302.0
Gencode_5P_Dist_Putative                     3573066.85       119160.0
Gencode_3P_Dist_Putative                     3572028.51       113846.0
Gencode_5P_Dist_Pseudo                       1464746.13        89391.0
Gencode_3P_Dist_Pseudo                       1464300.39        89559.0
Gencode_TxStop_Dist                           467008.81        13620.5
Gencode_TxStart_Dist                          469003.28        14466.5
Gencode_5P.UTR_Dist                          1895998.62        20632.0
Gencode_1stExon_Dist                          469888.92        14690.5
KnownGene_3P_Dist                              95961.66        35383.5
KnownGene_5P_Dist                              91981.53        30811.5
Ensemble_5P_Dist                               91180.56        30538.0
Refseq_5P_Dist                                 99281.63        40438.0
mRNA_5P_Dist                                   53365.13        14371.5
mRNA_3P_Dist                                   52167.74        21032.0
Spliced.EST_5P_Dist                            17785.17         4382.5
Spliced.EST_3P_Dist                            15438.77         3429.0
CpG.UCSC_Isl_Dist                             103557.88        37561.0
CpG.AL_Isl_Dist                               898207.51        23379.5
Nhgri_Chip.GM_Dist                            868014.70        12672.5
UWDHS.CAP.GM_Dist                             542744.42        14619.5
UWDHS.QCP.GM_Dist                           19432272.26        95435.0
UWDHS.QCP.HeLa_Dist                         19425543.76        70639.5
UVaDnaRep.OriginsPred_Dist                    130620.97        42320.5
Sanger_ChipCenters.H3K4me1.GM_Dist             27210.01         9418.5
Sanger_ChipCenters.H3K4me1.HeLa_Dist          492642.72        19149.5
Sanger_ChipCenters.H3K4me2.GM_Dist             33665.36        11641.5
Sanger_ChipCenters.H3K4me2.HeLa_Dist         2576216.73        40758.5
Sanger_ChipCenters.H3K4me3.GM_Dist             45577.31        16121.0
Sanger_ChipCenters.H3K4me3.HeLa_Dist         3421519.31        36910.5
Sanger_ChipCenters.H3ac.GM_Dist                79352.23        29398.0
Sanger_ChipCenters.H3ac.HeLa_Dist            2477835.05        50289.0
Sanger_ChipCenters.H4ac.GM_Dist                66446.61        25656.0
Sanger_ChipCenters.H4ac.HeLa_Dist            1498605.73        45795.0
Uva_DnaRep.Early_Dist                        9315695.24       120328.0
Uva_DnaRep.Mid_Dist                          5191078.39        55501.0
Uva_DnaRep.Late_Dist                          552794.68        70411.5
Uva_DnaRep.PanS_Dist                         5129837.44       173276.0
MSA_non.exonic_Dist                             6877.00          998.0