Annotation results

SangerChip data, H3ac, HeLa, 64kb wavelet smooth data, 2-state segmentation

  • Number of segments
    • State 0: 69
    • State 1: 57
  • Total size (bp)
    • State 0: 17347931
    • State 1: 12509943
  • Avg. segment length
    • State 0: 251419
    • State 1: 219473
  • Median segment length
    • State 0: 175999
    • State 1: 127999
  • Minimum segment length
    • State 0: 14999
    • State 1: 20999
  • Maximum segment length
    • State 0: 1036999
    • State 1: 737999

Gene overlap

Bed files below contain one line for each gene whose Tx start sits inside the given state. Columns are chr, start, stop, gene ID, fraction of gene sitting inside the segment, strand, and segment ID

  1. KnownGene
  2. Gencode.Known
  3. Ensembl

Enrichment of various elements

Total number of bases or elements overlapping each state. Numbers in parentheses are the fractions of the element in that state. Second set of columns gives enrichment over expected (as a fraction). Enrichment p-values, computed by permuting state labels on the fixed segmentation, are also included, with adjusted p-values using method "BH".

Element                                                     st0                    st1     st0 enr    st0 enr p    st0 adj p     st1 enr    st1 enr p    st1 adj p
-------------------------                  --------------------   --------------------   ---------   ----------   ----------   ---------   ----------   ----------
Num_Gencode_TxStarts                                645 (0.228)           2188 (0.772)      -0.608            0            0       0.843            0            0
Num_mRNA_TxStarts                                   924 (0.191)           3911 (0.809)      -0.671            0            0       0.931            0            0
Num_Spliced.EST_TxStarts                          17604 (0.127)         120771 (0.873)      -0.781            0            0       1.083       0.0001    0.0002909
EST_Ovr                                        10061831 (0.517)        9402217 (0.483)      -0.110       0.0038       0.0064       0.153       0.0006     0.001477
CpG.UCSC_Isl_Ovr                                  71197 (0.180)         323782 (0.820)      -0.690            0            0       0.957            0            0
RptMskr_Ovr                                     7654161 (0.570)        5765053 (0.430)      -0.018       0.1422       0.1422       0.025       0.1166       0.1204
RptMskr_DNA_Ovr                                  526093 (0.640)         296305 (0.360)       0.101       0.0063       0.0096      -0.140       0.0024     0.004267
RptMskr_LINE.L1_Ovr                             2803611 (0.672)        1367542 (0.328)       0.157       0.0009     0.002057      -0.217       0.0004     0.001067
RptMskr_LINE.L2_Ovr                              637733 (0.634)         367365 (0.366)       0.092       0.0215      0.02867      -0.128       0.0138       0.0192
RptMskr_LTR_Ovr                                 1394577 (0.666)         699746 (0.334)       0.146        0.001     0.002133      -0.203            0            0
RptMskr_SINE.ALU_Ovr                            1374171 (0.359)        2452149 (0.641)      -0.382            0            0       0.530            0            0
SimpRep_Ovr                                      307972 (0.410)         442957 (0.590)      -0.294       0.0013     0.002447       0.408       0.0013     0.002447
MSA_strict_Ovr                                   360216 (0.503)         356115 (0.497)      -0.135       0.0661      0.07051       0.187       0.0382      0.04527
MSA_moderate_Ovr                                 767268 (0.520)         709365 (0.480)      -0.106       0.0638       0.0704       0.147       0.0375      0.04527
MSA_loose_Ovr                                   1905571 (0.540)        1622414 (0.460)      -0.070       0.0533      0.06091       0.098       0.0286      0.03661
MSA_non.exonic_Ovr                               630174 (0.700)         269720 (0.300)       0.205       0.0122      0.01775      -0.285       0.0047      0.00752

(Postscript version of above)

Distances of elements to segment boundaries

Results for each boundary

Average and median absolute value over all boundaries.

Statistic                                      avg(|d|)       med(|d|)
-------------------------                  ------------   ------------
Gencode_5P_Dist_Known                        2557230.28        21439.5
Gencode_3P_Dist_Known                        2560447.88        22187.5
Gencode_5P_Dist_Putative                     4464656.36       104988.0
Gencode_3P_Dist_Putative                     4463219.09       107559.5
Gencode_5P_Dist_Pseudo                       1390835.83        95436.0
Gencode_3P_Dist_Pseudo                       1390609.51        95801.0
Gencode_TxStop_Dist                           441613.16        12636.0
Gencode_TxStart_Dist                          442721.29        13816.0
Gencode_5P.UTR_Dist                          2568916.02        20632.0
Gencode_1stExon_Dist                          443558.81        14756.0
KnownGene_3P_Dist                             117341.49        35887.0
KnownGene_5P_Dist                             108840.14        37063.0
Ensemble_5P_Dist                              107637.83        36076.0
Refseq_5P_Dist                                104569.73        42503.5
mRNA_5P_Dist                                   60034.51        16307.0
mRNA_3P_Dist                                   57813.65        20684.5
Spliced.EST_5P_Dist                            17356.55         4289.0
Spliced.EST_3P_Dist                            15761.02         3515.5
CpG.UCSC_Isl_Dist                             112152.55        45614.5
CpG.AL_Isl_Dist                              1629685.31        27134.0
Nhgri_Chip.GM_Dist                           1602433.46        16015.5
UWDHS.CAP.GM_Dist                             512835.31        19607.5
UWDHS.QCP.GM_Dist                           22087952.22        86250.5
UWDHS.QCP.HeLa_Dist                         22079863.37        60065.0
UVaDnaRep.OriginsPred_Dist                    125082.62        41671.0
Sanger_ChipCenters.H3K4me1.GM_Dist             24892.74         9343.5
Sanger_ChipCenters.H3K4me1.HeLa_Dist          472887.23        16484.0
Sanger_ChipCenters.H3K4me2.GM_Dist             32649.84        12655.0
Sanger_ChipCenters.H3K4me2.HeLa_Dist         3220164.16        45724.5
Sanger_ChipCenters.H3K4me3.GM_Dist             47053.32        21073.5
Sanger_ChipCenters.H3K4me3.HeLa_Dist         4011606.46        42801.0
Sanger_ChipCenters.H3ac.GM_Dist                70713.96        37032.5
Sanger_ChipCenters.H3ac.HeLa_Dist            3121863.40        46491.0
Sanger_ChipCenters.H4ac.GM_Dist                60910.96        29215.5
Sanger_ChipCenters.H4ac.HeLa_Dist            2206643.03        47000.5
Uva_DnaRep.Early_Dist                       10905695.75       106836.0
Uva_DnaRep.Mid_Dist                          4621761.80        43447.5
Uva_DnaRep.Late_Dist                          574775.77        71415.5
Uva_DnaRep.PanS_Dist                         5848003.40       162881.5
MSA_non.exonic_Dist                            10628.11         1452.0