Annotation results

MSA non-exonic, 3kb sliding window, 64kb wavelet smooth data, 2-state segmentation

  • Number of segments
    • State 0: 72
    • State 1: 57
  • Total size (bp)
    • State 0: 18317635
    • State 1: 11680425
  • Avg. segment length
    • State 0: 254412
    • State 1: 204920
  • Median segment length
    • State 0: 149000
    • State 1: 146000
  • Minimum segment length
    • State 0: 22000
    • State 1: 14000
  • Maximum segment length
    • State 0: 1353000
    • State 1: 1000000

Gene overlap

Bed files below contain one line for each gene whose Tx start sits inside the given state. Columns are chr, start, stop, gene ID, fraction of gene sitting inside the segment, strand, and segment ID

  1. KnownGene
  2. Gencode.Known
  3. Ensembl

Enrichment of various elements

Total number of bases or elements overlapping each state. Numbers in parentheses are the fractions of the element in that state. Second set of columns gives enrichment over expected (as a fraction). Enrichment p-values, computed by permuting state labels on the fixed segmentation, are also included, with adjusted p-values using method "BH".

Element                                                     st0                    st1     st0 enr    st0 enr p    st0 adj p     st1 enr    st1 enr p    st1 adj p
-------------------------                  --------------------   --------------------   ---------   ----------   ----------   ---------   ----------   ----------
Num_Gencode_TxStarts                               2141 (0.754)            697 (0.246)       0.235       0.0082      0.01544      -0.369       0.0015        0.004
Num_mRNA_TxStarts                                  3972 (0.821)            867 (0.179)       0.344       0.0165       0.0288      -0.540        0.001     0.002909
Num_Spliced.EST_TxStarts                         122986 (0.888)          15480 (0.112)       0.455       0.1022       0.1258      -0.713       0.0021     0.005169
EST_Ovr                                        12042688 (0.616)        7509845 (0.384)       0.009       0.4163       0.4441      -0.014       0.3938       0.4345
CpG.UCSC_Isl_Ovr                                 242005 (0.612)         153157 (0.388)       0.003       0.5034       0.5034      -0.005       0.5013       0.5034
RptMskr_Ovr                                     8838355 (0.654)        4685066 (0.346)       0.070            0            0      -0.110            0            0
RptMskr_DNA_Ovr                                  491104 (0.595)         334638 (0.405)      -0.026       0.2616        0.299       0.041       0.2162       0.2562
RptMskr_LINE.L1_Ovr                             2847306 (0.674)        1374555 (0.326)       0.104       0.0209      0.03344      -0.164       0.0045       0.0096
RptMskr_LINE.L2_Ovr                              580660 (0.576)         427098 (0.424)      -0.056       0.0915       0.1171       0.088       0.0484      0.06734
RptMskr_LTR_Ovr                                 1379636 (0.652)         737848 (0.348)       0.067       0.0614      0.08187      -0.105       0.0274      0.03985
RptMskr_SINE.ALU_Ovr                            2707925 (0.704)        1138380 (0.296)       0.153       0.0171       0.0288      -0.240       0.0053       0.0106
SimpRep_Ovr                                      571088 (0.759)         181502 (0.241)       0.243       0.0227      0.03459      -0.381       0.0035        0.008
MSA_strict_Ovr                                   261481 (0.365)         455640 (0.635)      -0.403            0            0       0.632            0            0
MSA_moderate_Ovr                                 579713 (0.392)         898834 (0.608)      -0.358            0            0       0.561            0            0
MSA_loose_Ovr                                   1650753 (0.467)        1885248 (0.533)      -0.235            0            0       0.369            0            0
MSA_non.exonic_Ovr                               200822 (0.223)         699838 (0.777)      -0.635            0            0       0.996            0            0

(Postscript version of above)

Distances of elements to segment boundaries

Results for each boundary

Average and median absolute value over all boundaries.

Statistic                                      avg(|d|)       med(|d|)
-------------------------                  ------------   ------------
Gencode_5P_Dist_Known                        2159070.23        19589.5
Gencode_3P_Dist_Known                        2159943.48        19048.0
Gencode_5P_Dist_Putative                     4198795.75       124916.0
Gencode_3P_Dist_Putative                     4196868.80       120627.0
Gencode_5P_Dist_Pseudo                       1986462.74       121319.0
Gencode_3P_Dist_Pseudo                       1986822.39       120063.5
Gencode_TxStop_Dist                           842334.69        11260.5
Gencode_TxStart_Dist                          843081.87        13284.0
Gencode_5P.UTR_Dist                          2185781.95        22385.0
Gencode_1stExon_Dist                          844114.00        14233.0
KnownGene_3P_Dist                             110242.37        46398.0
KnownGene_5P_Dist                             109699.67        40163.5
Ensemble_5P_Dist                              116013.51        40610.0
Refseq_5P_Dist                                124729.00        48029.0
mRNA_5P_Dist                                   68198.49        18958.5
mRNA_3P_Dist                                   62143.83        20485.5
Spliced.EST_5P_Dist                            18105.84         6189.5
Spliced.EST_3P_Dist                            17397.08         4627.0
CpG.UCSC_Isl_Dist                             129895.76        45480.5
CpG.AL_Isl_Dist                               854156.90        30025.5
Nhgri_Chip.GM_Dist                            817229.90        19234.0
UWDHS.CAP.GM_Dist                             811709.63        18747.0
UWDHS.QCP.GM_Dist                           22318053.23      9295562.0
UWDHS.QCP.HeLa_Dist                         22306996.50      9299898.0
UVaDnaRep.OriginsPred_Dist                     88622.56        39164.0
Sanger_ChipCenters.H3K4me1.GM_Dist             24554.33         8513.5
Sanger_ChipCenters.H3K4me1.HeLa_Dist          876823.12        23105.5
Sanger_ChipCenters.H3K4me2.GM_Dist             35113.01        14573.0
Sanger_ChipCenters.H3K4me2.HeLa_Dist         3459782.39        48873.0
Sanger_ChipCenters.H3K4me3.GM_Dist             50555.86        22047.5
Sanger_ChipCenters.H3K4me3.HeLa_Dist         4467545.76        42008.0
Sanger_ChipCenters.H3ac.GM_Dist                79100.35        30761.5
Sanger_ChipCenters.H3ac.HeLa_Dist            2829321.00        60100.5
Sanger_ChipCenters.H4ac.GM_Dist                63596.12        27589.5
Sanger_ChipCenters.H4ac.HeLa_Dist            1419487.88        49845.0
Uva_DnaRep.Early_Dist                        8367606.30       146867.0
Uva_DnaRep.Mid_Dist                          4448403.96        79087.0
Uva_DnaRep.Late_Dist                          388343.50        61577.0
Uva_DnaRep.PanS_Dist                         4797395.70       167171.0
MSA_non.exonic_Dist                             9521.50         3277.0